Triathlon™ Custom DNA Amplification Service

Large-Scale DNA Production:

Linear, double-stranded DNA
Labeled or unlabeled ends
Fully custom service
Extensive QA/QC available
Produced cell-free
Cost-effective alternative to plasmid (compare | more info) and oligo synthesis (more info).
Many common fragments in stock and ready to ship (more info).
Capable of producing to milligram and gram quantities.

The Triathlon™ is a patent-pending system invented by Vandalia Research to enable the mass production of specific, high-quality DNA sequences with the polymerase chain reaction (PCR), a thermo-chemical reaction that replicates DNA outside of a cell.

While PCR has many advantages for DNA manufacturing, there have been barriers because of thermal limitations with rapid heating and cooling of aqueous mixtures. Typically, generating large quantities of DNA using PCR requires that the reaction mixture be distributed into very small tubes for thermal cycling. The reaction mix is subsequently collected and combined before the DNA products can be used. The Triathlon™, however, scales a PCR reaction from the bench to an industrial production system.

The Triathlon™’s primary advantage is a continuous method for heating and cooling the PCR reagents, which facilitates processing unlimited volume without having to pool the products from multiple small tubes. This results in reduced labor, decreased turnaround time, and, most critically, a reduction in the number of opportunities for contamination. The Triathlon™ enables PCR to cost-effectively transition from research to production.

Vandalia Research is now capable of providing milligram and gram quantities of custom PCR-amplified DNA for a variety of applications. Working closely with customers allows Vandalia Research to respond rapidly to their novel applications for PCR products with a high-quality product and excellent turnaround time.

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